Endocrine Abstracts

Aim: To evaluate whether anthropometric indices and acanthosis nigricans can be useful markers for early detection of Insulin Resistance and Metabolic Syndrome (MetS) in overweight and obese children.Methods: Data from 510 prepubertal children (40% boys), 12.9% overweight and 87.1% obese with mean age 9.7±2.5 years were analyzed. Logistic regression analysis was used to investigate which factors were associated with HOMA-IR >3 and metabolic synd...

Case report: Hirsutism although common in acromegaly (24%) is not considered as the prevalent symptom of the disease. Here we describe a seventy-one year old woman with a 2-year history of hyperandronism and subtle acromegalic features (macroglossia, sleep apnea). Clinical examination showed hirsutism (Ferrimann-Gallwey score 20/34), acanthosis nigricans and mild clitoridomegaly. Blood examination revealed elevated IGF-1: 502 ng/ml (69–200 ng/ml) and standard oral glucose...